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The following clinical studies show the effectiveness and benefits of the ON-Q PainBuster Pain Relief System.

Click on this icon below to view an abstract of the clinical study.
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CV/CT View
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White PF, Rawal S, Latham P, Chi L. Use of a continuous local anesthetic infusion for pain managment after median sternotomy. Anesthesiology 2003;99(4):918-23.

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Dowling R, Thielmeier K, Ghaly A, Barber D, Boice T, Dine A. Improved pain control after cardiac surgery: results of a randomized double-blind clinical trial. J Thor CV Surg 2003;126(5):1271-8.

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Wheatley GH, et al. Improved pain management outcomes with continuous infusion of a local anesthetic after thoracotomy. J Thor CV Surg 2005;130(2):464-8.

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Koukis A. Use of continuous subcutaneous anesthetic infusion in cardiac surgical patients after median sternotomy. J Cardiothorac Surg, 2008; 3:2.

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Tirotta C, et al. A continuous incisional infusion of either levobupivacaine 0.25% or bupivacaine 0.25% in pediatric patients. Presented at ASA Annual Meeting. October 2005.

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General View
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Thorson A, et al. The ON-Q pain management system in the contol of post-operative pain in colon and rectal surgery. United European Gastroenterology Week, 2001.

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Morrison J, Jacobs, V. Reduction or elimination of postoperative pain medication after mastectomy through use of a temporarily placed local anaesthetic pump vs. control group. Zentralblatt fur Gynakologie 2003;125:17-22.

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Gupta A, Thorn S, Axelsson K, Larsson L, Goran A, Holmstrom B, and Rawal N. Postoperative pain relief using intermittent injections of 0.5% ropivacaine through a catheter after laparoscopic cholecystectomy. Anesth Analg 2002;95:450-456.

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Sanchez B, Waxman K. Local anesthetic infusion pumps improve postoperative pain after inguinal hernia repair. The American Surgeon 2004;70:1002-6.

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LeBlanc KA, Bellanger D, Rhynes VK, Hausmann M Evaluation of a continuous infusion of 0.5% marcaine via elastomeric pump for postoperative pain management following open inguinal hernia repair. J Am Coll Surg 2005;200(2):198-202.

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Schell S. Patient outcomes after axillary lymph node dissection for breast cancer: use of postoperative continuous local anesthesia infusion. J Surg Res 2006; 134(1):124-32.

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Vintar N, Pozlen G, Rawal N, Godec M and Rakovec, S. Incisional self-administratiojn of bupivacaine or ropivacaine provides effective analgesia after inguinal hernia repair. Can J Anesth 2002;49(5):481-6.

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Lau H, Patil NG, Lee F. Randomized clinical trial of postoperative subfascial infusion with bupivacaine following ambulatory open mesh repair of inguinal hernia. Dig Surg. 2003;20(4):285-9.

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Dine A, Johnson S, Saint John B. Reduced rates of surgical site infection with the use of continuous incisional infusions of local anesthetic with ON-Q PainBuster: a meta-analysis of clinical studies. Presented at International Conference on Surgical Infections September 2006, Stockholm, Sweden.

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Sidiropoulou T, et al. A prospective comparison of continuous wound infiltration with ropivacaine versus single-injection paravertebral block after modified radical mastectomy. Anesth Analg, 2008;106:997-1001.

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Cheong WK, et al. Randomized clinical trial of local bupivacaine perfusion versus parenteral morphine infusion for pain relief after laparotomy. British J Surg, 2001;88:357-9.

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Baig MK, et al. Use of the ON-Q pain management system is associated with decreased postoperative analgesic requirement: double blind randomized placebo pilot study. J Am Coll Surg, 2006;202:297-305.

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Singh J, Hum M, Cohen S, Liberman H, Thorson A, Dine A, and the MISS Study Group. Multicenter infection surveillance study comparing two types of postoperative pain management, surgical site using ON-Q® SilverSoaker™ and local anesthetics vs. systemic narcotics following colorectal procedures. Presented at 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). Chicago, IL. September 2007.

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OB/GYN View
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Givens A, Lipscomb G and Meyer N. A randomized trial of postoperative wound irrigation with local anesthetic for pain after cesarean delivery. Am J Obstet Gynecol. 2002;186:1181-91.

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Fredman, B et al. The analgesic efficacy of patient-controlled ropivacaine instillation after Cesarean delivery. Anesth Analg 2000;91:1436-1440.

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Zimberg S, Guillermo D, Seiler J, Neimark M. ON-Q pain relief system in elective abdominal hysterectomy surgery, a pilot clinical outcomes study evaluating length of stay, postoperative pain, narcotic analgesia use and impact on costs and adverse effects. Am J OBGyn 2002;99(4). Supplement.

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Shahin M, Sanders, L, and Sood. A. Phase II study of ON-Q pain management system in patients undergoing surgery for gynecologic malignancy. Presented at the 30th Annual Clinical Meeting of the Western Association of Gynecologic Oncologist. June 6-9, 2001. Sun Valley, ID.

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Gupta A, et al. Postoperative pain after abdominal hysterectomy: a double-blind comparison between placebo and local anesthetic infused intraperitoneally. Anesth Analg 2004;99:1173-9.

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Lavand'homme P, Roelants F, Waterloos H, DeKock MF. Postoperative analgesic effects of continuous wound infiltration with diclofenac after elective cesarean delivery. Anesthesiology 2007;106:1220-5.

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Ranta PO, et al. Incisional and epidural analgesia after caesarean delivery: a prospective, placebo-controlled, randomized clinical study. Intl J OB Anesth 2006;15:189-94.

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Tyagaraj K, et al. ON-Q pump infusion of ropivacaine at the incision for pain management after gynecological surgery. Presented at ASA Annual Meeting, October 2005.

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Dulemba JF, Medler-Pelzel. The ON-Q pain pump for pain relief after laparoscopic surgery. Presented at AAGL 35th Annual Meeting, November 2006.

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Powers L. The use of the ON-Q PainBuster for postoperative pain management in laparoscopic assisted vaginal hysterectomy patients. Presented at Medical Education Fountation of the American College of Osteopathic Obstetricians and Gynecologists. March 2007.

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Shen-Gunther J. ON-Q anesthetic pump in gynecologic oncology: feasibility study of a novel placement technique at an army hospital. Military Medicine, 2008;173:918-23.

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Orthopedics/Spine View
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Klein, S., et al. Interscalene brachial plexus block with a continuous catheter insertion system and a disposable infusion pump. Anesth Analg 2000:91:1473-1478.

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White PF, Issioui T, Rawal S, Skrivanek GD. The use of a continuous popliteal sciatic nerve block after surgery involving the foot and ankle: does it improve the quality of recovery? Anesth Analg 2003;97: 1303-1309.

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Singh K, et al. A prospective, randomized, double blind study evaluating the efficacy of postoperative continuous local anesthetic infusion at the iliac crest bone graft site after spinal arthrodesis. Spine 2005; 30:2477-83.

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Gottschalk A, Burnmeister MA, Radtke P, Kreig M et al. Continuous wound infiltration with ropivacaine reduces pain and analgesic requirement after shoulder surgery. Anesth Analg 2003;97: 1086-91.

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Ganapathy S, et al. Periarticular local anesthetic infusion with I-Flow elastomeric pump provides superb analgesia, reduces opioid use and facilitates early ambulation. Presented at ASA Annual Meeting, October 2005.

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Elder JB, Hoh DJ, Wang MY. Postoperative continuous paravertebral anesthetic infusion for pain control in lumbar spine fusion surgery. Spine 2008; 33(2):210-8.

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Fredrickson MJ, Ball CM, Dalgleish AJ. Successful continuous interscalene analgesia for ambulatory shoulder surgery in a private practice setting. Reg Anesth Pain Med 2008:33(2):122-8.

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Ganesh A, et al. Continuous peripheral nerve blockade for inpatient and outpatient analgesia in children. Anesth Analg 2007;105(5):1234-42.

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Urology View
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Patel V. The ON~Q Pain Management System to reduce narcotic requirement after hand assisted laparoscopic nephrectomy. American Urology Association Annual Meeting 2003 World Congress of Endourology. 2003.

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Tamaddon K, Santiago L, Bellman G. Use of a new pain control mechanism for postoperative analgesia after percutaneous nephrolithotomy. Presented at World Congress of EndoUrology and ESWL. 2000.

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Mistry S, Miles B, Lipshultz L. Use of continuous local anesthetic infusion pumps in urological surgery. Contemporary Urology 2004:12-13.

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Bariatric View
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Hilliard SM, McCarty TM, et al. Use of local anesthetic infusion catheter in laparoscopic roux-en-y gastric bypass patients. Presented at Southwest Surgical Congress, San Antonio, TX. April 2005.

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Cottam DR et al. A randomized trial of bupivacaine pain pumps to eliminate the need for patient controlled analgesia pumps in primary laparoscopic roux-en-Y gastric bypass. Obes Surg 2007;17:595-600.

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Sherwinter DA, et al. Continuous infusion of intraperitoneal bupivacaine after laparoscopic surgery: a randomized controlled trial. Obes Surg 2008 July (epub ahead of print).

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Plastics View
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Pacik PT. Pain management in augmentation mammaplasty: a randomized, comparative study of the use of a continuous infusion versus self-administration intermittent bolus of a local anesthetic. Aesthetic Surg Journal 2004;24:523-30.

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Spann MD, et al. Continuous bupivacaine wound perfusion following immediate tissue expander breast reconstruction. Presented at the 49th Annual Meeting of the Plastic Surgery Research Council. June 9-14, 2004.

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Heller L, Kowalski AM, Wei C, Butler CE. Prospective, randomized, double-blind trial anesthetic infusion and intravenous narcotic patient-controlled anesthesia pump for pain management after free tram flap breast reconstruction. Past Reconstr Surg 2008;122(4):1010-18.

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Economics View
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Zimberg S. Reducing pain and costs with innovative postoperative pain management. Managed Care Quarterly 2003;11(1):34-36.

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There are inherent risks in all medical devices, please refer to the product labeling for Indications, Cautions, Warnings and Contraindications.For example, failure to follow the product labeling regarding filling, flow rate selection and placement of the pump and/or catheter could directly impact patient safety. Physician is responsible for prescribing and administering medications per instructions provided by the drug manufacturer.